Xanax withdrawal usually starts a few hours after the last dose of the drug. The timeline inside follows a four-week process, with the first 1-3 days causing the worst symptoms, but most users will experiences symptoms of withdrawal to some degree for much longer than that. During medical detox from Xanax, the individual may first be switched to a longer-acting benzodiazepine, such as clonazepam or chlordiazepoxide. Longer-acting agents such as these are easier to manage throughout the ensuing benzodiazepine taper, and may help lessen the severity of the withdrawal symptoms. 3 Rebound anxiety and depression may occur during Xanax withdrawal. Symptoms may be exacerbated making withdrawal harder to treat. The body will go through flu like symptoms at first until the body has time to regulate normal functioning. It may be mentally draining to fix and regulate anxiety levels which go up and down. Taking time off work and expecting challenges with interpersonal. Depression and thoughts of suicide should also be closely watched for during benzodiazepine withdrawal.Xanax withdrawal can leave people feeling generally “out of sorts,” unable to control their emotions, irritable, and jumpy. Mood swings, nightmares, trouble concentrating, short-term memory loss, and hallucinations are also potential side effects of Xanax withdrawal. Support from mental. Xanax Withdrawal and Detox. Withdrawal from Xanax can be dangerous and should never be done without the supervision of medical professionals. Luckily, effective medical detox options are available to help you recover from the effects of Xanax abuse. Benzodiazepine withdrawal syndrome—often abbreviated to benzo withdrawal—is the cluster of symptoms that emerge when a person who has been taking benzodiazepines, either medically or recreationally, and has developed a physical dependence, undergoes dosage reduction or discontinuation. Panic and anxiety Xanax is often prescribed in response to panic-related disorders, so many people are familiar with panic attacks. For some individuals, panic attacks first occur during withdrawal. When someone prescribed Xanax attempts to stop use, feelings of depression and anxiety may manifest during withdrawal. Individuals are likely to continue feeling the effects of Xanax withdrawal for 5–14 days after quitting Xanax. While the symptoms can peak during days one through four, they are often felt for a number of days beyond that. Anxiety and insomnia are still expected symptoms of the withdrawal process at this point. Xanax is calming and can help with things like insomnia, but it’s not typically recommended for use during opiate withdrawal unless instructed by a medical professional. Xanax increases the effects of GABA, which is a calming brain neurotransmitter.